Product safety aspects of plant molecular farming

Advances in plant molecular farming.

Plant molecular farming (PMF) is a new branch of plant biotechnology, where plants are engineered to produce recombinant pharmaceutical and industrial proteins in large quantities. As an emerging subdivision of the biopharmaceutical industry, PMF is still trying to gain comparable social acceptance as the already established production systems that produce these high valued proteins in microbia...

Plant Breeding and Molecular Farming

Molecular farming of Plant Derived Edible Vaccines

Plant Derived Edible Vaccines Abstract Vaccines have been one of the most farreaching and important public health initiatives of the 20 century. Edible vaccine, in particular, might overcome some of the difficult of production, distribution and delivery associated with traditional vaccine. Transgenic potatoes expressing LT-B were found to induce both serum and secretory antibodies when fed to m...

Plant molecular farming: opportunities and challenges.

Production of foreign molecules in transgenic plants is anticipated to be an alternative to already established, microbial or animal expression systems with lower production costs. This article reviews the different technologies and approaches currently used to produce economically interesting molecules in plants or plant cell cultures, to evaluate their technical feasibility and economic impli...

Catalytic Molecular Walkers: Aspects of Product Release

We study a model of multi-legged catalytic molecular walkers that abstract a class of recently developed synthetic molecular motors. We focus on their kinetics of release of catalytic product, delineating the influence of chemical kinetic parameters, geometric configuration, loss from surface, and bulk kinetics. We show that such walkers can achieve a uniform rate of release over long time scal...